Centuries in the making, the US-12 Heritage Trail is a road connecting man, animals, commerce, culture, and nature. Bridging southern Michigan's east and west shores, the US-12 Heritage Trail is an unconventional destination that encourages the traveler to journey its winding roads, meet its people, explore its places, and uncover its hidden treasures.

US-12 (Michigan Avenue) through Saline follows the route of the historic Sauk Trail, a Native American trail that was to later become the Detroit and Chicago Road. Orange Risdon the founder of Saline was the original surveyor for the Detroit and Chicago Road. The portion of Michigan Avenue in Saline designated as a Heritage Route has several historic attractions. The old Schuyler Mill (now Weller's) is located near the intersection of US-12 and the Saline River. Henry Ford converted this Mill in 1937 to a soybean processing plant for the manufacture of auto paint and auto parts. The Saline downtown area is historically significant and vibrant. Oakwood Cemetery, Curtiss Mansion and the Rentschler Farm museum are other important attractions.

US-12 (Michigan Avenue) through Saline follows the route of the historic Sauk Trail, a Native American trail that was to later become the Detroit and Chicago Road. Orange Risdon the founder of Saline was the original surveyor for the Detroit and Chicago Road. The portion of Michigan Avenue in Saline designated as a Heritage Route has several historic attractions. The old Schuyler Mill (now Weller's) is located near the intersection of US-12 and the Saline River. Henry Ford converted this Mill in 1937 to a soybean processing plant for the manufacture of auto paint and auto parts. The Saline downtown area is historically significant and vibrant. Oakwood Cemetery, Curtiss Mansion and the Rentschler Farm museum are other important attractions.